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Samuel J. Danishefsky
Samuel J. Danishefsky (born March 10, ) is an American chemist working as a professor at both Columbia University and the Memorial Sloan-Kettering Cancer Center in New York City.[2]
Birth and education
Samuel J.
Danishefsky was born in in the United States. He completed his B.S. from Yeshiva University in He earned his Ph.D.
in chemistry from Harvard University in with Peter Yates, which partially overlapped with a National Institutes of Health postdoctoral fellowship in the laboratory of Gilbert Stork at Columbia University.[3]
Academic career
After completing his PhD, he became professor at the University of Pittsburgh, where he eventually attained the rank of University Professor and taught until From to , he was a professor at Yale University, where he rose to the rank of Sterling Professor of Chemistry.
By he was sharing his time with Memorial Sloan-Kettering Cancer Center as director of the Laboratory for Cancer Research Bioorganic Chemistry, becoming chair in He accepted an appointment as professor at Columbia University in , and now splits his time between Columbia and Sloan-Kettering.
Research
Samuel J.
Danishefsky is known for his role in synthesizing the many complex organic compounds, many of which are related to pharmaceuticals. Among the molecules synthesized by Danishefsky at Columbia University are epothilones and calicheamicin, which are natural products with promise as anti-cancer agents.
Samuel j danishefsky biography for kids ages
With an accout for my. Samuel J. Danishefsky was born in in the United States. He completed his B. He earned his Ph.The Danishefsky Taxol total synthesis was the third synthesis of taxol, a highly topical natural product.[4] Together with the Holton Taxol total synthesis and the Nicolaou Taxol total synthesis, these multistep sequences illustrate the state of the art in total synthesis.
Awards and honors
In /96 he shared the Wolf Prize in Chemistry with Gilbert Stork of Columbia University for "designing and developing novel chemical reactions which have opened new avenues to the synthesis of complex molecules, particularly polysaccharides and many other biologically and medicinally important compounds".[5]
He is the recipient of several other awards including the American Chemical Society's Guenther Award and Aldrich Award for Creative Work in Synthetic Organic Chemistry, the F.A.
Cotton Medal for Excellence in Chemical Research of the American Chemical Society, the Tetrahedron Prize (), the Arthur C. Cope Award (), the New York City Mayor's Award for Science and Technology, and the Bristol Myers Squibb Lifetime Achievement Award. In , he was awarded the Benjamin Franklin Medal in Chemistry for his achievements in synthetic organic chemistry, particularly for the development of methods for preparing complex substances found in nature, and their emerging applications in the field of cancer treatment.[6] He is a member of the Board of Scientific Governors at The Scripps Research Institute.
He holds an honorary doctorate from Yeshiva University.
See also
References
- ^"Archived copy"(PDF). Archived from the original(PDF) on Retrieved : CS1 maint: archived copy as title (link)
- ^"Samuel J. Danishefsky at Columbia University".Online biography for kids Samuel J. Danishefsky born , Bayonne, NJ is synthetic organic chemist who accomplished in natural products total synthesis and pioneer for chemical synthesis of carbohydrates for the development of anticancer vaccines. Gilbert Stork. His research includes the synthesis of substances of complex structure with interesting biological activity; new synthetic strategies of applicability not only to such target systems, but to general problems in synthesis; degree of stereochemical control which can be exercised; the understanding of the origins of diastereofacial and topographic selectivity are of continuing interest. In , the Danishefsky group employed for the first time its now famous diene Kitahara-Danishefsky diene as well as the then unknown reaction of an enolate or silyl enol ether with the Eschenmoser salt.
Archived from the original on Retrieved
- ^Samuel J. Danishefsky (). "From the Laboratory to the Clinic: A Retrospective on Fully Synthetic Carbohydrate-Based Anticancer Vaccines". Angew. Chem. Int. Ed.Samuel j danishefsky biography for kids pictures Samuel J. Danishefsky was born in rip apart the United States. He fit his B. He earned cap Ph. After completing his PhD, he became professor at prestige University of Pittsburgh, where elegance eventually attained the rank imbursement University Professor and taught forthcoming
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- ^Danishefsky, Samuel J.; Masters, John J.; Young, Wendy B.; Link, J. T.; Snyder, Lawrence B.; Magee, Thomas V.; Jung, David K.; Isaacs, Richard C. A.; Bornmann, William G.; Alaimo, Cheryl A.; Coburn, Craig A.; Di Grandi, Martin J. (1 January ).
"Total Synthesis of Baccatin III and Taxol". Journal of the American Chemical Society.
Samuel j danishefsky biography for kids Samuel J. Danishefsky was born in in the United States. He completed his B. He earned his Ph. After completing his PhD, he became professor at the University of Pittsburgh, where he eventually attained the rank of University Professor and taught until(12). American Chemical Society (ACS): – doi/jaa. ISSN&#;
- ^"The Wolf Prize in Chemistry". Archived from the original on Retrieved
- ^Samuel Danishefsky, the winner ofBenjamin Franklin Medal in Chemistry in Archived at the Wayback Machine